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Prediction of Maximal Exercise Capacity in Obstructive and Restrictive Pulmonary Disease: Discussion (5)

Many factors could influence the relationship between lung function and exercise capacity. Some of these are related to technical factors such as the mode of exercise, work rate increments, and the length of the sampling interval during data collection. Patient variables of importance, in addition to pulmonary function, include motivation, … Continue reading

Prediction of Maximal Exercise Capacity in Obstructive and Restrictive Pulmonary Disease: Discussion (4)

Conversely, Kelley and Daniele reported on an r value of 0.74 between MW and VEmax in 20 patients with sarcoidosis. Although we found as have others that there was a significant relationship between Deo and Vo2max, Risk and colleagues reported that there was no correlation between the degree of reduction … Continue reading

Prediction of Maximal Exercise Capacity in Obstructive and Restrictive Pulmonary Disease: Discussion (3)

There are many equations in the literature that predict VEmax from resting pulmonary function data. These have been reviewed by Carter et al. They found that the best equations were those that used a zero intercept model, and in their patient sample, the equation 37.5 X FEV, gave the best … Continue reading

Prediction of Maximal Exercise Capacity in Obstructive and Restrictive Pulmonary Disease: Discussion (2)

In the study by Mahler and Harver, stepwise multiple regression revealed that the FEV,, age, and the baseline dyspnea index were the best predictors. Whereas Mahler and Harver did not find that the Dl added to the value of the predictive equation, they found in contrast to Carlson and coworkers … Continue reading

Prediction of Maximal Exercise Capacity in Obstructive and Restrictive Pulmonary Disease: Discussion (1)

Although our study showed significant correlations between indices of expiratory airflow and exercise function in patients with COPD, the confidence intervals were wide, making individual predictions inaccurate. Moreover, stepwise multiple linear regression to include other predictive variables did not appreciably improve the estimates. Although the correlation coefficients were higher in … Continue reading

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