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Prediction of Maximal Exercise Capacity in Obstructive and Restrictive Pulmonary Disease: Discussion (1)

Although our study showed significant correlations between indices of expiratory airflow and exercise function in patients with COPD, the confidence intervals were wide, making individual predictions inaccurate. Moreover, stepwise multiple linear regression to include other predictive variables did not appreciably improve the estimates. Although the correlation coefficients were higher in … Continue reading

Prediction of Maximal Exercise Capacity in Obstructive and Restrictive Pulmonary Disease: Results (2)

Tables 4 and Table 5 show correlation coefficients for prediction of VEmax and Vo2max, respectively, in the three severity subsets of patients with airway obstruction. As seen previously, the measures of expiratory flow correlate most closely with measures of peak exercise capacity. Also apparent is the significantly higher r value … Continue reading

Prediction of Maximal Exercise Capacity in Obstructive and Restrictive Pulmonary Disease: Results (1)

Anthropometric and resting pulmonary function data for all obstructed, the three subsets of severity, and the patients with restrictive disease are shown in Table 1. The mean FEV,/FVC ratio ranged from 67 percent in the mild group to 35 percent in the severely obstructed group. As expected the FVC, maximum … Continue reading

Prediction of Maximal Exercise Capacity in Obstructive and Restrictive Pulmonary Disease: Methods (2)

Incremental Exercise Studies Exercise studies were performed with the patient seated upright on an electrically braked cycle ergometer (Gould Goddart). All studies were performed with the patients breathing room air. The patient started with a 3-rnin period of unloaded cycling, after which the load was incremented by 10 to 20 … Continue reading

Prediction of Maximal Exercise Capacity in Obstructive and Restrictive Pulmonary Disease: Methods (1)

Study Population We retrospectively analyzed resting pulmonary function tests (PFTs) and incremental exercise studies collected over a 7-year period. We selected patients with obstructive disease based on an FEV/FVC of grater than one confidence interval (95 percent) below the normal predicted mean. These patients were further subdivided into mild, moderate, … Continue reading

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